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Gwenalle Le Pavec and Agns Delaunay-Moisan for their help in using the microplate reader

Patients usually present with menstrual pain (dysmenorrhea) and/or infertility problems (151153)

Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors

These markers included increased plasma alanine and lactate levels and the presence of organic acids, such as 3-methyl-glutaconic and dicarboxylic acids, and Krebs cycle intermediates, in the urine of these patients [69]

Current knowledge of PCD is largely based on hallmark signaling pathways, such as BAX-mediated mitochondrial apoptosis and GPX4-mediated ferroptosis